3D Arterial Spin Labeling. Non-contrast, whole brain, quantitative perfusion assessment. No needle. No ionizing radiation.

3D Arterial Spin Labeling (3D ASL) delivers quantitative perfusion assessment—without radiation or need for an IV line.

It's simple and fast, too. With automated image postprocessing, results are available instantaneously. Use 3D ASL to help you reliably rule out focal or global perfusion defects in a wide population, including geriatric and pediatric patients, or:

  • Evaluate tumors
  • Assess stroke, TIA, stenoses, and other cerebrovascular diseases
  • Evaluate neurodegenerative diseases
  • Image structural vasculature problems

3D ASL uses water in arterial blood as an endogenous contrast media to help visualize tissue perfusion and provide quantitative assessment of cerebral blood flow (CBF) in ml/100 g/min. A GE-pioneered new pulsed-continuous arterial spin labeling method (aka Pseudo-Continuous ASL) helps generate more signal and improve contrast. GE 3D FSE with spiral readout further helps increase signal-to-noise ratio (SNR), while minimizing motion and reducing susceptibility artifacts, compared to conventional gradient echo -based techniques. 3D ASL helps generate robust, reproducible images and perfusion maps with high SNR, reduced motion artifacts, and less distortion in regions of high-magnetic susceptibility.

"We currently perform ASL on all patients with suspected or known cerebrovascular disease. The 3D FSE readout permitted the visualization of small structures… In several cases the 3D ASL images have increased our confidence or suggested an unexpected, alternative diagnosis"      

Greg Zaharchuk, MD,    
Stanford Radiology, CA 


Understand how 3D ASL produces reliable whole-brain perfusion coverage with improved SNR.

Download 3D ASL Ready for Clinical Use.

Read how 3D ASL provides you with more accurate quantification of brain-tissue perfusion.

Download Advances in Non-Contrast Enhanced Perfusion Assessment.

Try it Now

Try 3D ASL now!

Have your system ID ready, then click on your MR platform to begin your software download. You'll have 30 days to try it for free. Like it? Buy it. Not for you? We'll deactivate it.

Get Started

Note: System software level 16.0 or higher is required for Signa HDxt and VIBRANT. For upgrade options, contact your sales representative directly or fill out a contact form.


MR scanning has not been established as safe for imaging fetuses or infants. Carefully compare the benefits of MR versus alternative procedures before scanning to control risk to the patient. A physician needs to decide to scan pregnant or infant patients.

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