Marquette™ 12SL ECG analysis program

Connected. Clinical. Excellence.

Acute Coronary Syndrome (ACS)

Improve sensitivity of acute ischemic syndrome interpretation

Serial comparison

Consistent, validated1 analysis ensures reproducibility and objectivity

QT algorithm

Dependable, reproducible and accurate measurement and interpretation

Pace statements

Detects bi-ventricular pacemakers and identifies underlying rhythm

Empowering you with clinical decision support for your ECG

Since its introduction in 1980, the Marquette 12SL has been consistently refined and improved in order to offer our customers the best possible clinically validated decision support to help achieve faster accurate diagnosis—for remote ECGs or third party ECGs.

Delivering precise measurement and accurate interpretation

The Marquette 12SL is continually refined through regular input from the world’s top consulting cardiologists and physicians and is validated against clinically-correlated databases for accuracy, with over 200 scientific references.2

Acute Coronary Syndrome (ACS)

The Marquette 12SL ACS tool* increases sensitivity for ST-Elevated MI or Acute Ischemia in patients suspected of having an acute cardiac event. 

The tool heavily weighs the finding of ST elevation with reciprocal ST depression. This is a very important and highly-specific indicator of STEMI and ACS that has been found to “identify patients who stand to benefit most from early interventional strategies.”3 

A study evaluated on over 1,900 clinically correlated ECGs from patients suspected of having ACS showed that the ACS tool improved the sensitivity of emergency physicians’ interpretation of acute myocardial infarction by 50% and cardiologists’ interpretations by 26%, with no loss of specificity.4


Serial comparison

The Marquette Serial Comparison Program indicates changes in the ECG from the previous ECG of the same patient. 

It utilizes interpretive statements, ECG measurements and waveform comparison techniques to maximize accuracy in the detection of clinically significant changes. 

Exceeding current standards for 12- and 15-lead measurements and analysis, it ensures reproducibility and objectivity for increased efficiency in the process. 

Serial comparison requires the MUSE™ ECG management system.


QT algorithm

It’s well recognized that the identification of prolonged QT is important, as the condition can result in serious arrhythmia and Sudden Cardiac Death.5 

However, it can be difficult to measure QT accurately due to factors such as ECG noise, difficulty defining the end of the T wave, and requiring corrections for heart rate. 

We’ve concentrated our efforts in helping to minimize these challenges through the Marquette 12SL program. 

The QT is measured from a median complex reducing the influence of noise, it’s also measured from global fiducial points from all 12 simultaneous leads. 


Pace statements

In conjunction with MAC VU360™, MAC™ 7, and MAC™ 5, the Marquette 12SL provides analysis for detecting bi-ventricular pacemakers, identifying the underlying rhythm, in addition to the chamber(s) being paced—sampling at a rate that is much greater than is required for conventional ECG analysis. 

The pacemaker annotation channel will then be displayed on the ECG printout and on the MUSE ECG management system.


Age and gender specific

Children are not the same as adults and neither are their ECGs. Equally, adult men and women are different and this difference extends to the ECG. 

The Marquette 12SL features Gender-Specific interpretation that applies criteria for evaluating the ST segment and T-wave of the ECG waveform to enhance diagnostic confidence. 

It improves the sensitivity for detection of acute anterior MI from 42% to 48% in women under 60 years of age,and has a 25% relative improvement in detection of acute inferior MI in women under 60.7

Accurate pediatric specific measurement and interpretation has been validated by an independent study with over 1,100 pediatric ECGs.8




Reduction in false positive admission of chest pain patients⁹


Reduction in CCU admission for non-AMI patients¹⁰


Increase in ECG interpretation accuracy¹¹

Up to 99%

ECG interpretation accuracy¹²


Stay ahead with the latest insights in diagnostic cardiology

Tailored to provide relevant, interesting, and informative articles allowing you to unlock the full power of the ECG to help you treat patients.

  • * The 12SL ACS algorithm is not available in all GE HealthCare ECG devices. MAC VU360 is not available in all markets. Contact your GE HealthCare Representative for more details.
  • 1, 8. Marquette™ 12SL ECG Analysis Program Physician’s Guide 2056246-002, 2015 General Electric Company.
  • 2. For more details please refer to the GEHC 12SL statement of validation and accuracy.
  • 3. Otto, L.A. and T.P. Aufderheide, Evaluation of ST segment elevation criteria for the prehospital electrocardiographic diagnosis for acute myocardial infarction. Ann Emerg Med, 1994. 23(1): p. 17-24
  • 4, 7. Xue, J., “A New Method to Incorporate Age and Gender Into the Criteria for the Detection of Acute Inferior Myocardial Infarction.” J Electrocardiol. 34(4) (Part 2) (Oct 2001): 229-234
  • 5. Al-Khatib SM, et. al., What Clinicians Should Know About the QT Intervall, Jama 2003; 289(16):2120-2127
  • 6. Wright, R.S., “Women with Acute Anterior Myocardial Infarction Have Less Precordial ST Elevation Than Men Independent of Age of Presentation.” J Am Coll Cardiol. 37(2001): 361A
  • 9, 10. Lee, T.H., et al., Impact of the availability of a prior electrocardiogram on the triage of the patient with acute chest pain. J Gen Intern Med, 1990. 5(5): p. 381-8.
  • 11, 12. GE HealthCare. (2019). Enhancing Efficiency Through a Regional Healthcare System.

Have a question? We’d love to hear from you.