Trabecular Bone Score

Enhance the Prediction of Patient Fracture Risk
Boost the Performance of Bone Densitometry and Add Value to Your Clinical Practice

TBS iNsight™ is new bone structure assessment technique that enhances identification of fracture risk.

TBS iNsight™ software installs on existing DXA scanners. It is a simple, rapid and reproducible method that seamlessly integrates into your workflow and estimates fracture risk based on determination of bone texture. The result is expressed as a Trabecular Bone Score.

Using AP spine data obtained during routine DXA exams, TBS iNsight™ produces a clinically significant1,2 fracture risk parameter. The result derives from a patented algorithm that evaluates pixel gray-level and spatial variations in the DXA scan, providing an indirect, yet highly correlated, index of bone microarchitecture that is independent of bone mineral density (BMD), clinical risk factors and FRAX®.

We also offer ‘FRAX Adjusted for TBS’, which is a FRAX® 10-year probability of fracture based on clinical risk factors, BMD, and TBS™. This feature was built based on a prospective study of more than 30,000 patients and cross-validated using meta-analysis of 17,800 women and men across 14 countries3,4

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1. Harvey NC, Gluer CC, Binkley N, McCloskey EV, Brandi ML, Cooper C, et al. Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice. Bone. 2015;78:216-24.
2. Silva BC, Broy SB, Boutroy S, Schousboe JT, Shepherd JA, Leslie WD. Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score. J Clin Densitom. 2015;18(3):309-30.
3. McCloskey EV, Oden A, Harvey NC, Leslie WD, Hans D, Johansson H, et al. A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX. J Bone Miner Res. 2016;31(5):940-8.
4. McCloskey EV, Oden A, Harvey NC, Leslie WD, Hans D, Johansson H, et al. Adjusting fracture probability by trabecular bone score. Calcif Tissue Int. 2015;96(6):500-9